The invention discloses a nasal drop for rhinitis treatment and a preparation method of the nasal drop for rhinitis treatment. The nasal drop is prepared from, by weight, 0.5-6 parts of folium artemisiae argyi, 1-5 parts of indigo naturalis, 2-11 parts of flos magnolia, 7-25 parts of herba houttuyniae, 3-11 parts of herba centipedae, 4-10 parts of cirsium setosum, 2-8 parts of trichosanthes kirilowii, 5-12 parts of mint, 1-5 parts of puberulous glochidion herb, 0.5-3 parts of solanum nigrum, 5-15 parts of semen cuscutae, 40-80 parts of black sesame and 3-14 parts of lotus seeds. Selected raw materials of the nasal drop are reasonable in compatibility, complementary in efficacy and excellent in synergistic effect, blood circulation and microcirculation of lesion parts can be improved, and curative effects of heat clearing, detoxifying, swelling relieving, sterilizing and radical curing are realized. The nasal drop has joint effects of wind-cold dispelling, nasal passage clearing, phlegm expelling and cough arresting and is applicable to treatment of rhinorrhoea, nasal congestion, cough, phlegm excessiveness and wind-cold headache caused by influenza. The nasal drop has the advantages of adoption of pure traditional Chinese medicine products simple to acquire, clear and definite components, convenience in use, safety, reliability, exact curative effects, less pain of patients, avoidance of surgeries, less side effects, low drug dependence, easiness for the patients to accept and great convenience for the patients.